ACST-2

ACST-1 Acknowledgements

The chief acknowledgement is to the patients who agreed to participate in this study. Funding was provided by the UK Medical Research Council and The Stroke Association, and free randomisation facilities and statistical support were provided by the University of Oxford Clinical Trial Service Unit.

ACST Collaborative Group

• Writing Committee – A Halliday (principal investigator), A Mansfield, J Marro, C Peto, R Peto, J Potter, D Thomas (principal neurological investigator).
• Steering Committee – M Brown, B Farrell, A Halliday, A Mansfield, R Peto, J Potter (chair), A Rau, D Thomas, C Wolfe.
• Data Monitoring Committee – R Collins, R Gray, J-M Orgogozo, C Warlow (chair).
• Endpoint Review Committee – R Foale, M Harrison (chair), C Jamieson, CV Ruckley.
• Clinical Trial Service Unit, Oxford – A Baxter, J Burrett, R Collins, J Godwin, S Knight, R Peto, A Radley, S Richards.
• Trial Office – A Baxter, S Byrd, A Clarke, M Emson, S Hamilton, E Hayter, D Kamugasha, J Marro, P Neave, C Peto, A Rau, P Robless, R Steele, J Wilcox

Collaborating Clinicians

• Austria (30 patients)
  • Innsbruck (G Fraedrich, C Schmidauer)
  • Vienna (TH Hölzenbein, G Kretschmer, V Metz, P Polterauer)
• Belgium (1 patient)
  • Antwerp (P Cras, P Van Schil)
• Brazil (2 patients)
  • Natal (G Gurgel)
• Bulgaria (6 patients)
  • Sofia (V Petrov, G Slabakov [deceased])
• Canada (30 patients)
  • Halifax (G Gubitz, R Holness, W Howes, R Langille, G MacKean, SJ Phillips, J Sullivan, J Wood)
• Croatia (2 patients)
  • Zagreb (T Sosa)
• Cyprus (13 patients)
  • Nicosia (NS Angelides, A Malikidou)
• Czech Republic (18 patients)
  • Pilzen (Z Ambler, J Polivka, J Simaná)
  • Prague (V Beneš, F Kramár)
• Finland (18 patients)
  • Helsinki (M Kaste, M Lepäntalo, L Soinne)
• France (2 patients)
  • Nimes (J-M Cardon, A Legallou)
• Germany (98 patients)
  • Augsburg (B Gengenbach, K Pfadenhauer, KD Wölfle)
  • Berlin (I Flessenkämper, BF Klumpp, J Marsch)
  • Düsseldorf (R Kolvenbach, T Pfeiffer, W Sandmann)
  • Freiburg (F Beyersdorf, A Hetzel, G Spillner)
  • Giessen (HJ Lutz)
  • Heidelberg (D Böckler, N Maeder)
  • Minden (O Busse, J Grönniger, F Haukamp)
  • Mülheim an der Ruhr (K Balzer, HG Knoob, G Roedig, L Virreira)
  • Würzburg (S Franke, R Moll, J Schneider)
• Greece (10 patients)
  • Athens (J Dayantas, MN Sechas, S Tsiaza)
  • Thessaloniki (D Kiskinis)
• Hungary (59 patients)
  • Budapest (A Apor, L Entz, K Hüttl, Z Jàrànyi, I Mogan, Z Nagy, A Szabo, D Varga)
  • Miskolc (G Juhász, L Mátyás)
• Ireland (7 patients)
  • Dublin (M Hutchinson, D Mehigan)
• Israel (245 patients)
  • Ashkelon (Z Aladjem, S Elmakias, B Yoffe,)
  • Haifa (H Ben-Meir, L Dagan, R Karmeli, G Keren, A Shimony, B Weller)
  • Petach Tikva (R Avrahami, A Koren, J Streifler, S Tabachnik, A Zelikovski)
• Italy (328 patients)
  • Bari (F Federico, L Pascazio, G Regina)
  • Bologna (E Pozzati)
  • Brescia (S Bonardelli, SM Giulini, B Guarneri)
  • Caserta (P Caiazzo)
  • Ferrara (F Mascoli)
  • Genova (G Becchi, G Canova, R Masini, E Santoro, G Simoni)
  • L'Aquila (L Cucciolillo, C Spartera, P Scarpelli, M Ventura)
  • Milano (O Arena, M Collice, M Puttini, F Romani, I Santilli, V Segramora, R Sterzi)
  • Padova (G Deriu, F Verlato)
  • Perugia (PG Cao, E Cieri, P De Rango, L Moggi, S Ricci)
  • Pescara (A Antico, F Spigonardo)
  • Reggio Emilia (G Malferrari, N Tusini, E Vecchiati)
  • Rome (A Cavallaro)
  • Savona (N Zinicola)
  • Torrette di Ancona (FP Alò, G Pagliariccio)
  • Torino (D Palombo, F Peinetti)
  • Trieste (R Adovasio, F Chiodo Grandi, G Mase)
  • Udine (V Fregonese, L Mozzon)
• New Zealand (10 patients)
  • Hamilton (R Blair, J Chuen, C Holdaway, F Shakibaie)
• Norway (47 patients)
  • Oslo (A Kroese, CE Slagsvold)
  • Trondheim (T Dahl, HJ Johnsen, HO Myhre)
• Poland (88 patients)
  • Katowice (J Gniadek)
  • Warsaw (P Andziak, M Elwertowski, A K Malek, J Mieszkowski, W Noszczyk, M Szostek)
• Portugal (13 patients)
  • Porto (C Correia, MC Pereira)
• Russia (10 patients)
  • Moscow (RS Akchurin)
• Slovenia (44 patients)
  • Maribor (V Flis, K Miksic, B Stirn, E Tetickovic)
• Spain (196 patients)
  • Barcelona (M Cairols, JM Capdevila, E Iborra-Ortega, V Obach, V Riambau, F Vidal-Barraquer, R Vila-Coll)
  • Coruna (E Diaz-Vidal, JI Iglesias-Negreia, A Tovar-Pardo, RJ Segura Iglesias)
  • Galdakao (AF Alfageme, A Barba, JC Garcia-Monco)
  • Palma (C Corominas, J Julia, P Lozano)
  • San Sebastian (JF Marti-Masso, RM Porta,)
  • Vigo (A Rosendo Carrera, J Gomez)
• Sweden (532 patients)
  • Göteborg (C Blomstrand, J Gelin, J Holm, L Karlström, E Mattsson)
  • Helsingborg (S Bornhov, J Dahlstrom, G De Pedis, SM Jensen, H Pärsson, G Plate, P Qvarfordt)
  • Kalmar (B Arvidsson, L Brattström, C Forssell, A Potemkowski, C Skiöldebrand, P Stoor)
  • Linköping (M Blomqvist, M Callander, C Forssell, F Lundgren)
  • Lund (H Almqvist, L Norgren, B Norrving, E Ribbe, J Thörne)
  • Malmö (A Gottsäter, T Mätzsch, ME Nilsson)
  • Norrkoping (C Forssell, M Lonsson, F Lundgren, B Stahre)
  • Örebro (L Norgren, B Stenberg)
  • Stockholm (P Konrad, L Lundqvist, P Olofsson, S Rosfors, C Skiöldebrand, J Swedenborg, R Takolander, N Wahlgren)
  • Uppsala (D Bergqvist, C Ljungman, H Pärsson)
• Switzerland (6 patients)
  • Bern (HW Kniemeyer, MK Widmer)
  • St Gallen (W Nagel, D Sege, B Weder)
• The Netherlands (132 patients)
  • Beverwijk (J De Nie, J Doelman, N Yilmaz)
  • Eindhoven (J Buth, G Stultiens)
  • Geldrop (J Boiten, A Boon, F van der Linden)
  • Leeuwarden (DC Busman, A Engström)
  • Rotterdam (HAW Sinnige, TI Yo)
  • Utrecht (BC Eikelboom, LJ Kappelle, RWH van Reedt Dortland, TE Westra)
• Tunisia (11 patients)
  • Montfleury (H Jaber, J Manaa, RB Meftah, BR Nabil, T Sraieb)
• United Kingdom (1069 patients)
  • Bath (D Bateman, J Budd, M Horrocks, M Kivela, L Shaw, R Walker)
  • Belfast (AAB Barros D'Sa, K Fullerton, R Hannon, J M Hood, B Lee, K McGuigan, J Morrow, J Reid, CV Soong)
  • Birmingham (M Simms)
  • Bristol (R Baird, M Campbell, S Cole, IT Ferguson, P Lamont, D Mitchell, A Sassano, FCT Smith)
  • Cambridge (PJ Kirkpatrick, P Martin, C Turner)
  • Cheshire (JF Clegg, M Crosley, J Hall)
  • Chester (L De Cossart, P Edwards, D Fletcher, S Rosser)
  • Dundee (PT McCollum, D Davidson, R Levison)
  • Edinburgh (AW Bradbury, RTA Chalmers, M Dennis, J Murie, CV Ruckley, P Sandercock)
  • Exeter (WB Campbell, T Frankel, C Gardner-Thorpe, N Gutowski, R Hardie, W Honan, P Niblett, A Peters, B Ridler, JF Thompson)
  • Glasgow (I Bone, G Welch)
  • Hereford (E C Grocott, P Overstall)
  • Huddersfield (MI Aldoori, BEA Dafalla)
  • Hull (J Bryce, C Clarke, PT McCollum, A Ming, AR Wilkinson)
  • Leeds (J Bamford, D Berridge, J Scott)
  • Leicester (RJ Abbott, R Naylor)
  • Liverpool (P Harris, P Humphrey)
  • London (M Adiseshiah, M Aukett, D Baker, CCR Bishop, A Boutin, M Brown, P Burke, KG Burnand, A Colchester, L Coward, AH Davies, M Espasandin, AEB Giddings, G Hamilton, M Harrison, C Judge, S Kakkos, A Mansfield, C McGuiness, A Nicolaides, TS Padayachee, H Riordan, E Sullivan, P Taylor, D Thomas, M Thompson, JHN Wolfe)
  • Manchester (CN McCollum, PA O'Neill, S Welsh)
  • Newcastle (J Barnes, M Davis, AD Mendelow, JE O'Connell, MSS Siddique, G Stansby, R Vivar)
  • Plymouth (S Ashley, C Cosgrove, J Gibson, DC Wilkins)
  • Southampton (ADB Chant, J Frankel, CP Shearman, J Williams)
  • Stirling (G Hall, R Holdsworth)
  • Truro (JN Davies, B McLean, KR Woodburn)
  • Wakefield (G Brown, P Curley, L Loizou)
• USA (16 patients)
  • Detroit (S Chaturvedi, F Diaz)
• Yugoslavia (77 patients)
  • Belgrade (D Radak, PR Todorovic